Dr. Glen Hofmann graduated from Northern Illinois University in 1972 with a B.S. in Chemistry and received his Ph.D. in Biophysics from Arizona State University in 1977. He went to medical school at the University of Louisville graduating in 1983 and finished his residency at the University of Cincinnati in Obstetrics in Gynecology in 1987.  Following his residency, he attended the Jones Institute in Norfolk, VA for his fellowship in Reproductive Endocrinology and Infertility, where they had the first baby born from IVF in the USA. He trained there with many of the pioneers in IVF.  

After his fellowship, he moved to join the IVF team at Mt. Sinai Hospital in New York, which had the largest and most successful donor egg program in the US at the time and participated in many of the fundamental research studies on ovum donation.  In the fall of 1992, Dr. Hofmann returned to Cincinnati to become the Medical Director of the Bethesda Fertility Center, a position that he held until June 2016.  Under his direction, and with his talents and leadership, he had led the Center to be the regional leader in IVF and ovum donation, with thousands of babies born from his efforts.  The Center was the first to achieve birth with IntraCytoplasmic sperm injection, use of testicular sperm for IVF, the only Center to freeze sperm in the shells of hamster eggs for men with very low sperm counts, routine blastocyst transfers, ultrasound-guided transfers, PreImplantation Genetic Diagnosis and Screening, and fertility preservation, being the only program in the Tri-State to achieve live births with non-fertilized frozen eggs.

Dr. Hofmann has over 60 peer-reviewed publications, ranging from studies in basic science, human implantation, and embryo uterine signaling.  Many of his clinical publications define how management of fertility patient care is done by all who practice IVF and ovum donation.  He is also an avid teacher, having residents and medical students participating in patient care in his clinical office.  His main areas of clinical interest are improving live birth rates in IVF and ovum donation, working to reduce multiple birth rates by offering elective single embryo transfer, and enhancing the availability and awareness of fertility preservation for women with cancer or just wishing to preserve their chance to have a family later in life.